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Related Experiment Videos

Spina bifida: epidemiological data from a pilot study.

J Jansen

    Acta Neurologica Scandinavica
    |February 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    This study reports a spina bifida incidence of 0.77 per 1000 births in Denmark. Surgical intervention improved survival rates, with three of ten operated children remaining handicap-free.

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    Area of Science:

    • Pediatrics
    • Epidemiology
    • Neurology

    Background:

    • Spina bifida epidemiology shows significant geographical variations.
    • A pilot project on infantile hydrocephalus registered a small group of patients.

    Purpose of the Study:

    • To determine the incidence of spina bifida in Vejle county, Denmark.
    • To analyze pregnancy outcomes and associated malformations in spina bifida patients.

    Main Methods:

    • Retrospective review of 22 spina bifida cases born between 1963-1969 in Vejle county.
    • Analysis of maternal pregnancy history and co-occurring congenital malformations.

    Main Results:

    • An incidence of 0.77 per 1000 births was recorded.
    • 54% of prior pregnancies resulted in normal viable infants.

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  • Seven patients had unrelated congenital malformations; all unoperated patients died.
  • Four of ten operated children survived to age 7-12 years, with three being handicap-free.

    • Conclusions:

    • The study provides incidence data for spina bifida in a specific Danish region.
    • Surgical intervention appears to improve outcomes for children with spina bifida.