beta-Hexosaminidase in serum from patients with cirrhosis and cholestasis

THe enzyme activity level of beta-hexosaminidase (beta-N-acetylglucosaminidase, EC 3.2.1.30; 2-acetamido-2-deoxy-beta-D-glucoside acetamidodeoxyglucohydrolase) in serum from patients with different forms of cirrhosis and cholestasis was found to be elevated. A comparison is also made with routine liver parameters. In the light of recent findings it seems probable that the increased level depends upon depressed clearance of this enzyme by the non-parenchymal cells in the liver.