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Malignant external otitis. Cure with adjunctive hyperbaric oxygen therapy.

J T Mader, J T Love

    Archives of Otolaryngology (Chicago, Ill. : 1960)
    |January 1, 1982
    PubMed
    Summary
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    Malignant otitis externa in a diabetic patient caused by Pseudomonas aeruginosa infection was resistant to antibiotics. Adjunctive hyperbaric oxygen therapy successfully resolved the infection.

    Area of Science:

    • Infectious Diseases
    • Hyperbaric Medicine
    • Otolaryngology

    Background:

    • Malignant otitis externa (MOE) is a severe infection of the external ear canal.
    • Diabetes mellitus is a common risk factor for MOE, often caused by Pseudomonas aeruginosa.
    • Antibiotic resistance can complicate MOE treatment.

    Observation:

    • A 55-year-old male diabetic patient presented with MOE.
    • The infection was refractory to high-dose moxalactam disodium therapy.
    • In vitro studies indicated sensitivity to moxalactam disodium.

    Findings:

    • Adjunctive hyperbaric oxygen therapy (HBOT) was added to the antibiotic regimen.
    • The patient's Pseudomonas aeruginosa infection resolved with the combined therapy.
    • HBOT demonstrated efficacy in treating antibiotic-refractory MOE.

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    Implications:

    • Hyperbaric oxygen therapy may be a valuable adjunctive treatment for severe, refractory malignant otitis externa.
    • This case highlights the importance of considering HBOT for diabetic patients with resistant Pseudomonas aeruginosa infections.
    • Further research into the role of HBOT in managing complex ear infections is warranted.