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Character of changes in the serum proteins of continuously irradiated rats
Using quantitative two-dimensional immunoelectrophoresis, the authors studied, at various intervals, changes in the serum prealbumin, albumin, A1-globulin A1-macroglobulin (A1M), haptoglobin, haemopexin, transferrin, immunoglobulin G (IgG) and C3 component of complement in rats irradiated continuously with daily input doses of 957 mGy, 1,914 mGy and 3,828 mGy up to the lethal dose. During irradiation with these inputs, the prealbumin, albumin, A1-globulin, A1M, transferrin, IgG and C3 levels fell while the serum haptoglobin and haemopexin concentration rose.
Using quantitative two-dimensional immunoelectrophoresis, the authors studied, at various intervals, changes in the serum prealbumin, albumin, A1-globulin A1-macroglobulin (A1M), haptoglobin, haemopexin, transferrin, immunoglobulin G (IgG) and C3 component of complement in rats irradiated continuously with daily input doses of 957 mGy, 1,914 mGy and 3,828 mGy up to the lethal dose. During irradiation with these inputs, the prealbumin, albumin, A1-globulin, A1M, transferrin, IgG and C3 levels fell while the serum haptoglobin and haemopexin concentration rose.