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Partial cystectomy for transitional cell carcinoma of the bladder
Scandinavian Journal of Urology and Nephrology
|January 1, 1984
Summary
Partial cystectomy offers a viable treatment for bladder carcinoma, with survival rates of 47.1% at 5 years. Tumor grade significantly impacts outcomes, highlighting the importance of this factor in surgical planning.
Area of Science:
- Urology
- Oncology
Background:
- Partial cystectomy has been utilized for urothelium-derived bladder carcinoma.
- This retrospective analysis examines outcomes from 1958-1978.
Purpose of the Study:
- To evaluate the efficacy and outcomes of partial cystectomy for bladder cancer.
- To identify prognostic factors influencing patient survival and recurrence.
Main Methods:
- Retrospective review of 55 patients who underwent partial cystectomy.
- Analysis of tumor grade, T-stage, tumor size, operative mortality, survival rates, and recurrence patterns.
Main Results:
- Operative mortality was 7.3%; 5-year and 10-year survival rates were 47.1% and 35.4%, respectively.
- Higher tumor grade (I/II vs. III/IV) and lower T-stage (T1 vs. T2/T3) correlated with significantly better survival.
- Tumor recurrence occurred in 58% of patients, predominantly within 2 years post-operation.
Conclusions:
- Partial cystectomy is a treatment option for bladder carcinoma, avoiding urinary diversion.
- Prophylactic antibiotics are recommended to reduce operative morbidity and mortality.
- Tumor grade and stage are critical prognostic indicators for patients undergoing partial cystectomy.