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Hepatitis B surface antigen in human tears
Archives of Ophthalmology (Chicago, Ill. : 1960)
|April 1, 1978
Summary
Hepatitis B virus (HBV) is increasingly transmitted among healthcare workers. This study found hepatitis B surface antigen in tears, indicating a risk via contaminated medical equipment like tonometers and contact lenses.
Area of Science:
- Virology
- Infectious Diseases
- Ophthalmology
Background:
- Hepatitis B virus (HBV) infection incidence is rising in the US, especially among healthcare professionals.
- Transmission routes beyond blood exposure, including respiratory, fecal-oral, and venereal, are suggested by epidemiological data.
- Hepatitis B surface antigen (HBsAg) has been detected in various body secretions, hinting at broader transmission possibilities.
Purpose of the Study:
- To investigate the presence of hepatitis B surface antigen (HBsAg) in the tears of infected individuals.
- To assess the potential for HBV transmission through ocular exposure or contaminated ophthalmic instruments.
Main Methods:
- Tears were collected from patients with confirmed HBsAg-positive serum.
- Collected tear samples were tested for the presence of HBsAg using appropriate diagnostic methods.
Main Results:
- Hepatitis B surface antigen (HBsAg) was detected in tears from 50% of the HBsAg-positive patients studied.
- This finding supports the presence of HBV in ocular secretions.
Conclusions:
- Tears can be a potential source of hepatitis B virus transmission.
- There is a demonstrable risk of transmitting HBV through contaminated tonometers or soft contact lenses.
- Ocular secretions should be considered in the context of HBV transmission, particularly in healthcare settings.