Relapsing polychondritis with multifocal neurological abnormalities.

Area of Science:

• Rheumatology and Neurology
• Autoimmune Disorders
• Clinical Case Study

Background:

• Relapsing polychondritis is an uncommon inflammatory disorder affecting cartilaginous tissues.
• It is frequently associated with audiovestibular dysfunction and, less commonly, unilateral facial weakness.

Observation:

• A 65-year-old woman presented with relapsing polychondritis, exhibiting auricular chondritis, ocular inflammation, and audiovestibular dysfunction.
• This patient uniquely displayed bilateral facial weakness and cerebral manifestations.

Findings:

• This case represents the first documented instance of relapsing polychondritis with bilateral facial nerve palsy.
• The patient's cerebral manifestations are also novel findings in the context of this disease.

Implications:

• This case broadens the understanding of the neurological complications associated with relapsing polychondritis.
• Highlights the importance of considering central nervous system involvement in patients with this rare autoimmune condition.