Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Direct temperature measurement.

P Fessenden, E R Lee, T V Samulski

    Cancer Research
    |October 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Accurate temperature assessment is crucial for advancing clinical hyperthermia. Current methods offer limited spatial coverage, hindering effective tumor treatment and patient outcomes.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    RADON SURVEY IN SCHOOL AND ESTIMATION OF EFFECTIVE DOSE USING CORRECTED RADON CONCENTRATION.

    Radiation protection dosimetry·2017
    Same author

    Early cathepsin K degradation of type II collagen in vitro and in vivo in articular cartilage.

    Osteoarthritis and cartilage·2016
    Same author

    Clinical and microbiological effects of a subantimicrobial dose of oral doxycycline on periodontitis in dogs.

    Veterinary journal (London, England : 1997)·2015
    Same author

    Geographical distribution of indoor radon and related geological characteristics in Bonghwa County, a provisional radon-prone area in Korea.

    Radiation protection dosimetry·2014
    Same author

    A sub-Tenon's capsule injection of lidocaine induces extraocular muscle akinesia and mydriasis in dogs.

    Veterinary journal (London, England : 1997)·2012
    Same author

    Riboswitches in eubacteria sense the second messenger cyclic di-GMP.

    Science (New York, N.Y.)·2008
    Same journal

    Inhibiting PPM1D Perturbs Mitochondrial Integrity to Stimulate cGAS-STING Signaling and Antitumor Immunity.

    Cancer research·2026
    Same journal

    BRD9 Degraders Unleash GBAF Chromatin Remodeling Activity in Synovial Sarcoma.

    Cancer research·2026
    Same journal

    Virtual Tumors Enable Prediction of Personalized Therapeutic Combinations for Non-Small Cell Lung Cancer.

    Cancer research·2026
    Same journal

    Opportunities to enhance cancer research through advocate-researcher partnerships.

    Cancer research·2026
    Same journal

    EGFR N-Glycosylation Catalyzed by NDST2 Promotes Lenvatinib Resistance in Hepatocellular Carcinoma.

    Cancer research·2026
    Same journal

    Immune checkpoint blockade augments lymphodepleting chemotherapy-induced antitumor immunity by expanding effector CD8+ T cell clones.

    Cancer research·2026
    See all related articles

    Area of Science:

    • Oncology
    • Medical Physics
    • Biomedical Engineering

    Background:

    • Clinical hyperthermia requires precise temperature monitoring for efficacy.
    • Current invasive temperature measurement techniques present significant limitations.
    • Non-invasive methods for ultrasound and electromagnetic hyperthermia have advanced, providing temperature-time profiles.

    Purpose of the Study:

    • To evaluate the accuracy and limitations of current temperature assessment techniques in clinical hyperthermia.
    • To highlight the challenges in documenting achieved temperatures within tumor and normal tissue volumes.

    Main Methods:

    • Review of established clinical temperature measurement techniques for hyperthermia.
    • Analysis of spatial and temporal temperature profiling capabilities for ultrasound and electromagnetic modalities.

    Related Experiment Videos

  • Assessment of factors limiting measurement accuracy, including position uncertainty and thermal conduction.

    • Main Results:

    • Established techniques allow temperature-time profiles at numerous spatial points.
    • Accuracy is limited by position uncertainty, thermal conduction smearing, and artifactual heating (±0.2°C for electromagnetic, ±0.5°C for ultrasound).
    • Inadequate documentation of achieved temperatures in tumor and normal tissue volumes remains a significant hindrance.

    Conclusions:

    • Accurate temperature assessment is vital for the clinical progression of hyperthermia.
    • Current non-invasive techniques provide improved spatial and temporal data but have inherent accuracy limitations.
    • The primary challenge lies in documenting temperature coverage within target tissues, impacting treatment effectiveness.