Scintigraphic findings in large-cell lymphoma of the spleen: concise communication

The scintigraphic findings from eight patients who underwent splenectomy for splenomegaly secondary to diffuse large-cell lymphoma are described. Large focal photopenic areas were found in all cases, either solitary or multiple. The appearance is relatively typical for large-cell lymphoma, which should be strongly considered in a nontraumatized patient who presents with painful splenomegaly of unknown origin.