Related Experiment Video

Updated: Aug 13, 2026

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus
06:15

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus

Published on: March 6, 2019

Gastro-oesophageal reflux in Nigerian newborn infants

J C Odita, J A Omene, A A Okolo

    Tropical and Geographical Medicine
    |June 1, 1984
    PubMed

    Insights

    Neonatal gastro-oesophageal reflux, characterized by persistent vomiting, affects infants, especially those small for gestational age (SGA). Most infants responded well to conservative treatment, highlighting the importance of early diagnosis for these newborns.

    Area of Science:

    • Pediatrics
    • Gastroenterology
    • Neonatal Care

    Background:

    • Neonatal gastro-oesophageal reflux is a common condition presenting with persistent vomiting.
    • Infants small for gestational age (SGA) are disproportionately affected.

    Purpose of the Study:

    • To analyze cases of neonatal gastro-oesophageal reflux.
    • To evaluate diagnostic methods and treatment outcomes.

    Main Methods:

    • Retrospective analysis of 14 neonatal cases (1977-1982).
    • Utilized plain abdominal/chest radiographs and barium meal examinations.
    • Assessed response to conservative management.

    Main Results:

    • 11 neonates had significant gastro-oesophageal reflux.
    • No hiatus hernia, oesophagitis, or oesophageal stricture identified.
    • Over 80% of infants responded positively to conservative treatment.
    • Two deaths occurred.

    Conclusions:

    • Persistent vomiting in SGA newborns with normal abdominal radiographs suggests gastro-oesophageal reflux.
    • Early diagnosis and conservative management are effective for most cases.
    • Further investigation may be warranted if symptoms persist or worsen.

    More Related Videos

    Effect of Hyaluronic Acid 35 kDa on an In Vitro Model of Preterm Small Intestinal Injury and Healing Using Enteroid-Derived Monolayers09:36

    Effect of Hyaluronic Acid 35 kDa on an In Vitro Model of Preterm Small Intestinal Injury and Healing Using Enteroid-Derived Monolayers

    Published on: July 28, 2022

    Oral Gavage in Neonatal Mouse Pups and Functional Assessment of Gut Barrier Integrity Using Ussing Chambers07:18

    Oral Gavage in Neonatal Mouse Pups and Functional Assessment of Gut Barrier Integrity Using Ussing Chambers

    Published on: January 9, 2026

    Related Concept Videos

    Gastroesophageal Reflux Disease I: Meaning and Pathophysiology01:29

    Gastroesophageal Reflux Disease I: Meaning and Pathophysiology

    Gastroesophageal Reflux Disease (GERD) involves the recurrent backflow of the stomach or duodenal contents into the esophagus, leading to troublesome symptoms and potential esophageal mucosal damage. Although GERD is often referred to as a disease, it is more accurately described as a syndrome, as it encompasses a range of symptoms and complications rather than a singular pathological entity, impacting a large number of individuals as the most prevalent upper gastrointestinal problem. Roughly...
    Gastroesophageal Reflux Disease II: Clinical Features and Management01:29

    Gastroesophageal Reflux Disease II: Clinical Features and Management

    Gastroesophageal reflux disease, or GERD, is a persistent medical condition that affects many individuals worldwide. Its clinical manifestations can vary greatly, making diagnosis and management challenging for healthcare professionals. The following is a comprehensive overview of the clinical manifestations, assessment, and management strategies for GERD.
    Clinical Manifestations
    GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
    Esophageal Strictures-I: Introduction01:30

    Esophageal Strictures-I: Introduction

    Esophageal strictures involve abnormal narrowing or tightening of the esophagus. They vary in length and severity, ranging from mild constriction to complete obstruction, and are classified as benign (noncancerous) or malignant (cancerous).
    Etiology
    The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
    Enteral Nutrition I: Orogastric and Nasogastric Feeding01:26

    Enteral Nutrition I: Orogastric and Nasogastric Feeding

    Enteral nutrition delivers nutrients directly to the stomach or small intestine through a tube. This method is appropriate for patients who cannot eat but still have a functioning digestive system. It is also beneficial for individuals with swallowing difficulties, anorexia, malabsorption, or those who have undergone gastrointestinal (GI) surgery.
    Orogastric (OG) and nasogastric (NG) feeding are two standard methods used for enteral nutrition. Enteral nutrition is often preferred over...
    Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding01:15

    Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding

    Enteral nutrition encompasses various methods of delivering nutrition directly to the gastrointestinal (GI) tract, bypassing traditional oral intake. It is particularly beneficial for patients who cannot eat by mouth but have a functioning digestive system. Key methods include nasointestinal feeding, gastrostomy, and jejunostomy, each suited to different clinical scenarios based on the patient's needs and condition.
    Nasointestinal Feeding
    Nasointestinal feeding involves placing a tube through...
    Gastroesophageal Reflux Disease01:25

    Gastroesophageal Reflux Disease

    Gastroesophageal reflux disease (GERD) is the backward flow of stomach contents (acid, pepsin, or bile) into the esophagus, causing mucosal inflammation known as esophagitis. It results from failure of antireflux mechanisms, mainly the lower esophageal sphincter (LES), influenced by mechanical and physiological factors.Etiology and Risk FactorsGERD develops when LES function is weakened or when intra-abdominal pressure increases. Risk factors include aging, obesity, and sliding hiatal hernia,...