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Related Experiment Videos

[Estrogens and the psyche].

H Kopera

    Wiener Klinische Wochenschrift
    |June 8, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Oestrogens significantly impact brain functions and mental performance in humans, particularly during hormonal changes like menopause. While excess or deficiency clearly affects mood, therapeutic use is most established for deficiency-related psychic disturbances.

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    The dawn of hormone replacement therapy.

    Maturitas·1991

    Area of Science:

    • Neuroendocrinology
    • Psychiatry

    Context:

    • Animal studies suggest oestrogens influence brain function and psychic states.
    • Human data on oestrogen's effects on mental performance and behavior are limited.
    • The precise role of physiological oestrogen levels in human cognition remains debated.

    Purpose:

    • To review the evidence for oestrogen's effects on human psychic functions.
    • To differentiate between established and speculative oestrogenic influences on mental health.
    • To evaluate the therapeutic applications of oestrogen replacement therapy.

    Summary:

    • Oestrogen deficiency and excess are definitively linked to human psychic disturbances, especially during peri- and postmenopause.
    • Evidence for oestrogen's impact on non-sexual behavior and general mental performance is less conclusive.

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  • Oestrogen replacement therapy is well-supported for psychic issues in hypogonadism, post-castration, and climacteric states.

    • Impact:

    • Highlights the established therapeutic benefits of oestrogen for specific hormonal deficiencies.
    • Underscores the need for more research into oestrogen's role in age-related cognitive decline.
    • Clarifies the current understanding of oestrogen's complex relationship with human mental well-being.