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Semen analyses in adolescent diabetic patients.
Acta Diabetologica Latina
|April 1, 1984
Summary
Adolescent diabetes mellitus (DM) significantly impairs semen quality, reducing volume, motility, and morphology. Poor metabolic control and neuropathy worsen these effects, while testosterone levels remain unaffected.
Area of Science:
- Endocrinology
- Reproductive Medicine
- Diabetology
Background:
- Insulin-dependent diabetes mellitus (IDDM) can affect various bodily functions.
- The impact of IDDM on male reproductive health, particularly in adolescents, requires further investigation.
Purpose of the Study:
- To assess semen quality and plasma testosterone levels in adolescent patients with IDDM.
- To identify factors associated with impaired semen quality in diabetic adolescents.
Main Methods:
- Compared semen parameters (volume, count, motility, morphology) and plasma testosterone in 32 adolescent diabetics and age-matched controls.
- Analyzed data based on the presence of retinopathy, neuropathy, and metabolic control.
Main Results:
- Diabetic adolescents showed significantly lower semen volume, motility, and morphology, with higher seminal fructose and glucose.
- Neuropathy and poor metabolic control were associated with further deterioration of semen parameters and seminal fructose/glucose levels.
- Retinopathy did not correlate with semen quality or testosterone levels.
Conclusions:
- Adolescent IDDM leads to a decline in human semen quality.
- Neuropathy and poor metabolic control are key factors contributing to this decline.
- Testosterone levels and retinopathy are not significantly associated with semen quality changes in this cohort.