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Related Experiment Videos

[Plasma histamine level in anesthesia with enflurane].

K Kubo, M Oka

    Der Anaesthesist
    |June 1, 1984
    PubMed
    Summary

    Enflurane anesthesia did not significantly alter plasma histamine levels in oral surgery patients. This study investigated histamine responses during dental procedures under general anesthesia.

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    Area of Science:

    • Anesthesiology
    • Pharmacology
    • Biochemistry

    Context:

    • Oral surgery patients undergoing anesthesia.
    • Assessment of histamine release during surgical procedures.
    • Evaluation of enflurane's impact on physiological responses.

    Purpose:

    • To investigate plasma histamine levels during enflurane anesthesia in oral surgery.
    • To determine if enflurane anesthesia causes significant histamine release.
    • To establish a baseline histamine level for comparison.

    Summary:

    • Plasma histamine levels were measured in 14 oral surgery patients before and during enflurane anesthesia.
    • A fluorometric method with high-speed liquid chromatography was employed for histamine quantification.
    • No statistically significant difference was observed in plasma histamine levels.

    Impact:

    • Provides data on the safety of enflurane anesthesia regarding histamine release in oral surgery.
    • Contributes to understanding the physiological effects of anesthetic agents.
    • Informs clinical practice for patients undergoing oral surgery under general anesthesia.

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