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Exophthalmos in systemic lupus erythematosus
Annals of Ophthalmology
|July 1, 1984
Summary
Exophthalmos is rare in systemic lupus erythematosus (SLE). This study presents the first SLE patients with exophthalmos following pseudotumor cerebri, suggesting alternative treatments beyond corticosteroids.
Area of Science:
- Ophthalmology
- Rheumatology
- Neurology
Background:
- Systemic lupus erythematosus (SLE) is a chronic autoimmune disease.
- Exophthalmos, or bulging eyes, is an uncommon manifestation of SLE.
Observation:
- This study details the first reported cases of exophthalmos in SLE patients that were preceded by pseudotumor cerebri.
- The patients presented with exophthalmos subsequent to the diagnosis of pseudotumor cerebri.
Findings:
- Exophthalmos in SLE patients with a history of pseudotumor cerebri may not respond well to corticosteroid therapy.
- The observed cases highlight a unique clinical presentation linking these conditions.
Implications:
- Corticosteroids may be insufficient for managing exophthalmos in SLE patients with preceding pseudotumor cerebri.
- Alternative treatments like immunosuppressive agents, orbital irradiation, or plasmapheresis should be considered.
- This finding expands understanding of SLE's ocular and neurological complications.