Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Monitoring demyelination in multiple sclerosis with multi-flash campimetry.

P Mustillo, E M Brussell, C W White

    International Ophthalmology
    |June 1, 1984
    PubMed
    Summary

    Multi-flash campimetry helps distinguish demyelination from transient factors in multiple sclerosis (MS) patients. This technique monitors visual system changes, aiding in documenting progressive visual involvement in MS.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Avoidance of Profound Hypothermia During Initial Reperfusion Improves the Functional Recovery of Hearts Donated After Circulatory Death.

    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2016
    Same author

    Physiologic Changes in the Heart Following Cessation of Mechanical Ventilation in a Porcine Model of Donation After Circulatory Death: Implications for Cardiac Transplantation.

    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2015
    Same author

    Novel drug targets for the pharmacotherapy of benign prostatic hyperplasia (BPH).

    British journal of pharmacology·2011
    Same author

    Physiologic assessment of coronary artery stenosis severity.

    Trends in cardiovascular medicine·2011
    Same author

    Single-beam and enhanced two-beam second-harmonic generation from silicon nanocrystals by use of spatially inhomogeneous femtosecond pulses.

    Physical review letters·2005
    Same author

    Can early infection explain the sibling effect in adult atopy?

    The European respiratory journal·2003

    Area of Science:

    • Ophthalmology
    • Neuroscience
    • Medical Technology

    Background:

    • Multiple Sclerosis (MS) can cause visual disturbances due to optic nerve demyelination.
    • Multi-flash campimetry reveals 'islands' of reduced temporal resolution in MS patients.
    • Distinguishing demyelination from transient factors like edema is crucial for MS management.

    Purpose of the Study:

    • To differentiate between persistent demyelination and transient factors affecting visual function in MS patients.
    • To assess the reliability of multi-flash campimetry in monitoring MS progression.
    • To explore the utility of multi-flash campimetry in clinical practice for MS patients.

    Main Methods:

    • Utilized multi-flash campimetry, a computer-implemented psychophysical technique.

    Related Experiment Videos

  • Assessed visual flicker sensitivity in multiple sclerosis patients over several months.
  • Generated multi-flash field maps to analyze temporal resolution changes.

    • Main Results:

    • Identified 'islands' of degraded temporal resolution in MS patients, absent in controls.
    • Observed that persistent 'islands' over time likely indicate demyelination.
    • Suggested transient changes reflect other factors like inflammation or edema.

    Conclusions:

    • Multi-flash campimetry can differentiate demyelination from transient visual disturbances in MS.
    • The technique shows potential for documenting progressive visual involvement in MS.
    • Multi-flash campimetry may serve as a tool for monitoring the clinical course of visual demyelination in MS.