Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

ECG changes during lithium therapy. A prospective study.

G Bucht, L Smigan, A Wahlin

    Acta Medica Scandinavica
    |January 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Diagnosing Carotid Near-Occlusion with Phase-Contrast MRI.

    AJNR. American journal of neuroradiology·2021
    Same author

    Increase of frontal neuronal activity in chronic neglect after training in virtual reality.

    Acta neurologica Scandinavica·2018
    Same author

    Early death rates remain high in high-risk APL: update from the Swedish Acute Leukemia Registry 1997-2013.

    Leukemia·2017
    Same author

    Prevalence and characteristics of survivors from acute myeloid leukemia in Sweden.

    Leukemia·2016
    Same author

    Factors Influencing the Efficacy of Platelet Transfusions in Acute Leukemia.

    Leukemia & lymphoma·2016
    Same author

    Cerebrospinal fluid and blood flow patterns in idiopathic normal pressure hydrocephalus.

    Acta neurologica Scandinavica·2016
    Same journal

    On hereditary, non-hemolytic bilirubinemia.

    Acta medica Scandinavica·2010
    Same journal

    Infections with leukopenia treated with sulfa compounds.

    Acta medica Scandinavica·2010
    Same journal

    A peculiar conduction disturbance, persisting latently after recovery from complete heart block and disclosed only by electrocardiography following exercise.

    Acta medica Scandinavica·2010
    Same journal

    Titration with Weichbrodt's reagent of serum, particularly in the case of gall-liver diseases.

    Acta medica Scandinavica·2010
    Same journal

    Arthralgia due to nervous causes.

    Acta medica Scandinavica·2010
    Same journal

    Auricular standstill.

    Acta medica Scandinavica·2010
    See all related articles

    Long-term lithium treatment can cause T wave changes on electrocardiograms (ECGs) but generally not serious cardiac issues. Routine ECG monitoring is likely unnecessary for patients on well-managed lithium therapy without heart disease symptoms.

    Area of Science:

    • Cardiology
    • Psychopharmacology

    Background:

    • Lithium is a common mood stabilizer for bipolar disorder.
    • Long-term lithium use may affect cardiac function.
    • Electrocardiograms (ECGs) are used to assess heart electrical activity.

    Purpose of the Study:

    • To investigate the long-term effects of lithium treatment on ECG parameters.
    • To determine if routine ECG monitoring is necessary during lithium therapy.

    Main Methods:

    • Prospective study of 53 patients receiving long-term lithium therapy.
    • ECG recordings taken before, and at 4 and 12 months after starting lithium.
    • Analysis of ECG parameters including T wave, heart rate, P-Q interval, S-T segment, and corrected Q-T interval.

    Main Results:

    Related Experiment Videos

    • The most common ECG change was T wave flattening or inversion.
    • A slight decrease in heart rate and increase in P-Q interval were observed.
    • No significant changes in S-T segment or corrected Q-T interval occurred.
    • Serum lithium levels were maintained around 0.6 mmol/l.

    Conclusions:

    • Well-monitored lithium treatment at therapeutic levels (approx. 0.6 mmol/l) is not associated with serious ECG abnormalities.
    • Routine ECG monitoring may not be required for asymptomatic patients undergoing lithium therapy.
    • Observed ECG changes are generally benign and do not necessitate intervention in the absence of cardiac symptoms.