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Pneumococcal pneumonia with bacteraemia.

R A Banks, R C George, M W McNicol

    British Journal of Diseases of the Chest
    |October 1, 1984
    PubMed
    Summary
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    Pneumococcal pneumonia with bacteremia disproportionately affects older adults with underlying conditions. Streptococcus pneumoniae type 3 was most common, and renal failure was linked to fatal outcomes in this study.

    Area of Science:

    • Infectious Diseases
    • Pulmonology
    • Nephrology

    Background:

    • Pneumococcal pneumonia with bacteremia presents a significant health challenge, particularly in older populations.
    • Pre-existing conditions are frequently observed in patients with severe pneumococcal infections.
    • Streptococcus pneumoniae serotypes vary in their clinical impact and associated complications.

    Purpose of the Study:

    • To investigate the clinical characteristics, serotype distribution, and outcomes of pneumococcal pneumonia with bacteremia.
    • To identify risk factors and complications associated with severe pneumococcal pneumonia.
    • To evaluate the impact of renal complications on patient mortality.

    Main Methods:

    • Retrospective analysis of fourteen cases of pneumococcal pneumonia with bacteremia.

    Related Experiment Videos

  • Identification of pneumococcal serotypes responsible for infections.
  • Assessment of patient demographics, pre-existing conditions, and renal function.

    • Main Results:

    • Thirteen of fourteen patients were over 50 years old, with ten having pre-existing diseases.
    • Six pneumococcal serotypes were identified; type 3 was most prevalent and associated with three of four fatal cases.
    • Renal failure was present in all fatal cases and in eight of ten survivors, often presenting as treatable prerenal failure. Hyponatremia was common.

    Conclusions:

    • Pneumococcal pneumonia with bacteremia in older adults, especially those with pre-existing conditions, carries a high risk of morbidity and mortality.
    • Streptococcus pneumoniae type 3 and renal complications, including prerenal failure and hyponatremia, are significant factors influencing outcomes.
    • Despite prompt treatment, intensive care is often required, highlighting the severity of this condition.