Polyclonal orbital and systemic infiltrates

Two unusual cases of benign lymphoproliferative disease associated with orbital and systemic involvement are described. Both have occurred in adults with longstanding histories and clinical manifestations that have mimicked lymphomas. The orbital disease has been both antecedent and subsequent to the systemic lesions. These cases emphasize the spectrum of lymphoproliferative disorders and call attention to the possibility of multisystem disease in patients with benign lymphoproliferative lesions.