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Eosinophilic pustular folliculitis in infancy.

A W Lucky, N B Esterly, N Heskel

    Pediatric Dermatology
    |January 1, 1984
    PubMed
    Summary

    Infants can develop a distinct skin condition called eosinophilic pustular folliculitis, characterized by itchy, sterile pustules primarily on the scalp. This condition may also affect the trunk and extremities, presenting a unique pediatric dermatosis.

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    Area of Science:

    • Pediatric Dermatology
    • Dermatopathology

    Background:

    • Eosinophilic pustular folliculitis (EPF) is a rare inflammatory skin condition typically observed in adult patients.
    • Previous literature primarily describes scalp and trunk involvement in adult EPF.

    Observation:

    • Five infants under one year of age presented with recurrent, pruritic papulopustules predominantly affecting the scalp.
    • Three infants also experienced intermittent pustular outbreaks on the trunk and extremities.
    • Microbiological cultures of pustules were sterile.

    Findings:

    • Skin and scalp biopsies revealed eosinophilic folliculitis.
    • Peripheral eosinophilia was noted in some patients during pustular outbreaks.
    • The clinical presentation in infants differed from adult EPF due to predominant scalp involvement.

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    Implications:

    • The findings suggest a distinct pediatric variant of eosinophilic pustular folliculitis.
    • This condition represents a unique pustular dermatosis in infancy.
    • Further research is warranted to understand the pathogenesis and long-term outcomes of infantile EPF.