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Related Concept Videos

Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
Accessory Structures of the Skin: Sebaceous Glands01:21

Accessory Structures of the Skin: Sebaceous Glands

A sebaceous gland is a type of oil gland found almost all over the skin ( except palms and soles) and helps lubricate and waterproof the skin and hair. Most sebaceous glands are associated with hair follicles. They generate and excrete sebum, a mixture of lipids, onto the skin surface, thereby naturally lubricating the dry and dead layer of keratinized cells of the stratum corneum, keeping it pliable.
These glands that produce the oils on the skin and hair are holocrine glands. The mature...
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
The Skin Microbiota01:27

The Skin Microbiota

The human skin serves as a complex ecosystem inhabited by a diverse community of microorganisms, including bacteria, fungi, and viruses. This microbiome plays a critical role in maintaining skin health and defending against pathogenic invaders. The composition of microbial communities varies significantly across different regions of the body, influenced primarily by the local levels of moisture and sebum.Regional Variation in Skin MicrobiotaCutibacterium acnes predominantly colonizes sebaceous...
Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...

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Related Experiment Video

Updated: Jun 15, 2026

A Rat Model of Compound Acne
03:10

A Rat Model of Compound Acne

Published on: November 1, 2024

Acne.

B R Krafchik1

  • 1Division of Dermatology, The Hospital for Sick Children, University of Toronto, Toronto, Ontario.

Paediatrics & Child Health
|March 10, 2010
PubMed
Summary
This summary is machine-generated.

Acne affects adolescents and adults, impacting self-esteem and social life. Early and effective therapies are available to manage this common skin condition and prevent lasting emotional and physical effects.

Keywords:
Acne vulgarisPathogenesisTreatment

Related Experiment Videos

Last Updated: Jun 15, 2026

A Rat Model of Compound Acne
03:10

A Rat Model of Compound Acne

Published on: November 1, 2024

Area of Science:

  • Dermatology
  • Adolescent Medicine

Background:

  • Acne vulgaris is a prevalent skin condition affecting individuals across various age groups, including neonates, children, adolescents, and adults.
  • The condition commonly manifests on the face, chest, and back, leading to significant psychological distress such as embarrassment and social withdrawal.
  • Untreated or severe acne can result in long-term physical scarring and emotional sequelae.

Purpose of the Study:

  • To highlight the widespread impact of acne across different age demographics.
  • To emphasize the importance of early intervention in managing acne.
  • To inform about the availability of effective therapeutic options for acne treatment.

Main Methods:

  • This abstract is based on a review of current understanding and treatment modalities for acne.
  • It synthesizes information on the prevalence, impact, and management of acne vulgaris.

Main Results:

  • Acne is a common disease with a broad age range of presentation.
  • Psychological and social impacts are significant, affecting quality of life.
  • Effective treatments exist, mitigating the need for prolonged suffering.

Conclusions:

  • Early and appropriate treatment of acne is crucial for preventing physical and emotional complications.
  • Modern therapeutic strategies offer effective solutions, improving patient outcomes and reducing the historical burden of the disease.