Solution intolerance among users of four chemical soft lens care regimens

The incidence of solution intolerance in 161 soft contact lens patients was about 33% in those using chlorhexidine plus thimerosal chemical disinfecting systems. Those who disinfected their lenses with systems based primarily on thimerosal developed intolerance in 5 to 8% of cases. A family history of allergy appears not to be significant.