Infertility and chronic prostatitis.

Area of Science:

• Urology
• Andrology
• Infectious Diseases

Background:

• Chronic prostatitis affects male reproductive health, often presenting with subtle symptoms.
• Semen analysis frequently reveals leukocytospermia and oligoasthenozoospermia in affected individuals.
• The impact of chronic prostatitis on male infertility requires effective therapeutic strategies.

Purpose of the Study:

• To evaluate the efficacy of long-term antimicrobial therapy for chronic prostatitis.
• To assess the influence of this treatment on semen quality parameters.
• To determine the impact on male infertility and conception rates.

Main Methods:

• A cohort of 30 men with chronic prostatitis underwent 6-8 months of antimicrobial treatment.
• Treatment regimens included co-trimoxazole, doxycycline, and erythromycin.
• Semen analysis and clinical assessments were performed before and after treatment.

Main Results:

• Symptom improvement or cure was observed in 79.7% of patients.
• Pathogen eradication was achieved in 100% of cases.
• Spermatogram normalization or improvement occurred in 70%, leading to pregnancies in 9 couples.

Conclusions:

• Chronic prostatitis is a significant contributor to male infertility, particularly with semen leukocytosis and oligoasthenozoospermia.
• Long-term antimicrobial treatment effectively manages chronic prostatitis and improves male fertility.
• Investigating and treating chronic prostatitis is essential for infertile men with abnormal semen parameters.