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Intravenous extravasation injuries: the effectiveness of hyaluronidase in their treatment
Annals of Plastic Surgery
|September 1, 1984
Abstract:
This experimental study in the rabbit establishes a reliable model for the production of skin necrosis analogous to intravenous extravasation injuries in humans. The effectiveness of hyaluronidase in reducing the extent of tissue injury is examined, using several different toxic agents.