A case of fatal strychnine poisoning

Although rare today, poisoning from strychnine, both intentional and accidental, still occurs. A fatal case of self-poisoning with a strychnine preparation is presented. The case illustrates the dramatic presentation of strychnine poisoning, its rapidity of action, and the need for early aggressive treatment. The discussion centers on the pharmacokinetics, the mechanism of action, the signs and symptoms, and the treatment of poisoning from strychnine. The need for rapid diagnosis and the current recommended therapy for this poison are discussed.