Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pancreatic function testing in cystic fibrosis.

P R Durie, K J Gaskin, M Corey

    Journal of Pediatric Gastroenterology and Nutrition
    |January 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Why do clinical guidelines for probiotics differ?

    Beneficial microbes·2024
    Same author

    Comment on 'Determination of Bifidobacterium and Lactobacillus in breast milk of healthy women by digital PCR'.

    Beneficial microbes·2016
    Same author

    (13)C mixed triglyceride breath testing using infrared spectrometry: comparison of two devices in early infancy.

    European journal of clinical nutrition·2016
    Same author

    Children after fontan have strength and body composition similar to healthy peers and can successfully participate in daily moderate-to-vigorous physical activity.

    Pediatric cardiology·2014
    Same author

    The role of probiotics and prebiotics in the prevention of infections in child day-care centres.

    Beneficial microbes·2014
    Same author

    Meta-analysis: Lactobacillus reuteri strain DSM 17938 (and the original strain ATCC 55730) for treating acute gastroenteritis in children.

    Beneficial microbes·2014
    Same journal

    Constipation outcomes in children with and without autism spectrum disorder: Insights from a tertiary motility service.

    Journal of pediatric gastroenterology and nutrition·2026
    Same journal

    Heterogeneous outcomes in pediatric potential celiac disease: A multicenter longitudinal study.

    Journal of pediatric gastroenterology and nutrition·2026
    Same journal

    Inter-tissue relationships of gene expression in liver, muscle and adipose tissue of children with end-stage chronic liver disease.

    Journal of pediatric gastroenterology and nutrition·2026
    Same journal

    Foreign body ingestions in children and adolescents: A position paper of the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN) endoscopy special interest group.

    Journal of pediatric gastroenterology and nutrition·2026
    Same journal

    Abdominal pain in pediatric immunoglobulin A vasculitis: Risk factors and severity predictors in a multicenter cohort.

    Journal of pediatric gastroenterology and nutrition·2026
    Same journal

    Cognitive assessment in children with intestinal failure on and weaned off parenteral nutrition.

    Journal of pediatric gastroenterology and nutrition·2026
    See all related articles

    Current methods for measuring pancreatic function in cystic fibrosis (CF) patients are not ideal. New, sensitive indirect tests are needed to accurately assess pancreatic function, especially in those with pancreatic sufficiency.

    Area of Science:

    • Gastroenterology
    • Pulmonology
    • Biochemistry

    Background:

    • Assessing pancreatic function is crucial for managing cystic fibrosis (CF).
    • Current clinical techniques for measuring pancreatic function in CF patients are suboptimal.
    • Accurate assessment is particularly challenging for patients with pancreatic sufficiency.

    Purpose of the Study:

    • To review the limitations of current clinical techniques for measuring pancreatic function in CF patients.
    • To highlight the need for improved diagnostic methods for exocrine pancreatic function in CF.

    Main Methods:

    • Review of existing literature on pancreatic function tests in CF.
    • Analysis of the accuracy and limitations of direct and indirect pancreatic function tests.
    • Evaluation of blood tests for monitoring pancreatic function.

    Related Experiment Videos

    Main Results:

    • Direct pancreatic stimulation tests are accurate but invasive and complex, limiting routine use.
    • Indirect tests can identify patients with complete pancreatic insufficiency but lack sensitivity for those with pancreatic sufficiency.
    • Blood tests like immunoreactive trypsinogen show potential but require further longitudinal studies.

    Conclusions:

    • No current clinical technique is ideal for measuring pancreatic function in all CF patients.
    • There is a critical need for more sophisticated indirect tests to adequately assess exocrine pancreatic function in CF.
    • Improved methods are essential for monitoring pancreatic health and guiding treatment in CF patients.