[Intramuscular administration of Prostin for abortion in the second trimester]

The effect of Prostin (15/S/15 methyl prostaglandin F2 alpha) ampules applied intramuscularly to induce abortion in the second trimester of pregnancy was investigated. Out of 30 women who underwent the treatment, 28 (93.3%) cases were successful and 2 (6.7%) unsuccessful. The average time from the application of the medicament to the output of the ovulum was 30.04 hours. The medicament proved to have a strong uterotonic effect associated with highly manifested side effects, such as vomiting, diarrhea, nausea, perspiration, etc. Among serious complications due to the Prostin application, a single case of an incomplete low uterine rupture and one case of the cervical rupture (6.6%) were evidenced.