[Combined treatment of breast cancer using bremsstrahlung and electron radiation]

Combined therapy with accelerator high-energy radiations was applied to 116 patients with breast cancer, Stages II-III. At the beginning the patients received preoperative irradiation of the affected breast and ipsilateral axillary zone with braking irradiation at 25 MeV. The summary focal dose of 20 Gy was delivered with 5 daily fractions, 4 Gy each. This was followed by radical mastectomy. In the postoperative period irradiation of the supraclavicular and parasternal zones on the ipsilateral side with electron radiation at 10-22 McV was used when indicated. The summary focal dose of 44-50 Gy was provided in 22-25 fractions. Local recurrences developed in 2.6% of the cases. No regional recurrences and metastases to the supraclavicular lymph nodes were noted. No marked reactions and complications were revealed.