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Published on: January 28, 2020
Prognosis of cardiac disease in the ambulant patient
Insights
Unexpected cardiac death is uncommon in cardiology patients. Most cardiac deaths occurred in elderly patients with advanced disease and prior symptoms, with no unexpected fatalities observed in this study.
Area of Science:
- Cardiology
- Clinical Medicine
- Epidemiology
Background:
- Cardiac practice often assumes unexpected death is common in patients.
- This assumption guides intensive diagnostic and therapeutic interventions.
- The study questions the prevalence of unexpected cardiac mortality.
Purpose of the Study:
- To evaluate the actual incidence of unexpected death in ambulant cardiac patients.
- To determine if current cardiac care assumptions are evidence-based.
- To assess the potential impact of interventions on mortality rates.
Main Methods:
- A cohort of 636 consecutive ambulant cardiac patients was studied from 1978 to 1981.
- Mortality data, including cause and circumstances of death, were meticulously recorded.
- Patient demographics, disease status, and initial symptoms were analyzed.
Main Results:
- Only 22 deaths (3.4%) occurred in the study cohort over the observation period.
- Nineteen of these deaths were attributed to cardiac causes.
- All cardiac deaths were in elderly patients with advanced, long-standing disease and prior symptoms, none being unexpected.
Conclusions:
- Unexpected death is relatively uncommon in cardiology practice.
- Current intensive regimens for younger, asymptomatic patients with cardiomyopathy and coronary disease may not significantly impact overall mortality.
- Further research may be needed to refine risk stratification and treatment strategies.
Abstract:
Much investigation and treatment in cardiac practice is based on the assumption that unexpected death is common in cardiac patients. The validity of this assumption was examined in 636 of 669 (95.1%) consecutive ambulant patients. During the period from 1978 to 1981, inclusive, 16 (3.9%) of the 407 men (median age, 52 years) and six (2.6%) of the 229 women (median age, 54 years) died. Nineteen of these 22 patients died of cardiac causes; most of these were elderly (average age, 68.5 years), had advanced cardiac disease for many years before their death, and complained of breathlessness at the initial interview. None of these deaths was unexpected. It is concluded that unexpected death is relatively uncommon, even in cardiology practice. The intensive diagnostic and therapeutic regimens directed at younger patients with cardiomyopathy and coronary disease who do not complain of breathlessness are unlikely to have an appreciable impact on mortality.
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