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Multiple pilomatricomas (calcifying epitheliomas of Malherbe)
Pediatric Dermatology
|July 1, 1984
Summary
Multiple pilomatricoma, a rare skin condition, can present with numerous lesions. One patient developed a record 10 nodules over four years, highlighting the potential for extensive disease presentation in pilomatricoma.
Area of Science:
- Dermatology
- Pathology
- Oncology
Background:
- Pilomatricoma is a benign skin neoplasm originating from hair follicle matrix cells.
- Multiple pilomatricoma, while uncommon, presents a diagnostic and management challenge.
- Literature review indicates a need for further understanding of extensive pilomatricoma cases.
Purpose of the Study:
- To report three cases of multiple pilomatricoma.
- To document the highest reported number of pilomatricoma lesions in a single patient.
- To review existing literature on multiple pilomatricoma.
Main Methods:
- Case series presentation of three patients with multiple pilomatricoma.
- Detailed clinical description of lesion presentation and progression.
- Comprehensive literature search for similar cases.
Main Results:
- Three patients with multiple pilomatricoma were identified.
- One patient presented with 10 sporadic pilomatricoma nodules over a four-year period.
- This represents the largest number of lesions documented in an individual to date.
Conclusions:
- Multiple pilomatricoma can manifest with a significant number of lesions.
- The case series contributes to the understanding of pilomatricoma's variable presentation.
- Further research is warranted to explore potential underlying factors in extensive pilomatricoma.