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Influence of DL-2-phenyl[6-ethoxybenzothiazolyl-(2)-thio]propionic acid (EMD 34853) on gallstone formation in
Pharmacological Research Communications
|February 1, 1984
Abstract:
The effects of two levels (50 and 167 mg/kg) of a new hypocholesterolemic drug (EMD 34853) on gallstone formation in hamsters were investigated. Lithogenicity was inhibited by 28-45%. Levels of biliary lipids (cholesterol, phospholipid, bile acids) were reduced in the drug-treated animals.