Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Is 0.5% bupivacaine solution isobaric?].

D N Mihic

    Regional-Anaesthesie
    |July 1, 1984
    PubMed
    Summary

    Bupivacaine 0.5% administered via subarachnoid injection exhibits hypobaric properties, influenced by patient positioning. Body position significantly affects the spread of spinal anesthesia, with sitting positions leading to higher dermatome levels.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Optimal regional anaesthesia for abdominal hysterectomy: combined subarachnoid and epidural block compared with other regional techniques.

    European journal of anaesthesiology·1993
    Same author

    [Postspinal headaches, needle surfaces and longitudinal orientation of the dural fibers. Results of a survey].

    Regional-Anaesthesie·1986
    Same author

    Is the application of an Esmarch bandage justified?

    Anesthesiology·1984
    Same author

    [Avoiding hypoxemia during anesthesia].

    Der Anaesthesist·1983
    Same author

    [Fatal lung embolism following ischemia and peridural anesthesia].

    Regional-Anaesthesie·1983
    Same author

    [The 1st orotracheal intubation].

    Der Anaesthesist·1983

    Area of Science:

    • Anesthesiology
    • Pharmacology

    Context:

    • Subarachnoid anesthesia involves injecting drugs into the cerebrospinal fluid.
    • Patient positioning is a critical factor influencing anesthetic spread and efficacy.
    • Understanding drug characteristics, like baricity, is essential for predictable outcomes.

    Purpose:

    • To investigate the baricity of bupivacaine 0.5% when administered via subarachnoid injection.
    • To determine the influence of immediate post-injection body position on the spread of subarachnoid bupivacaine.

    Summary:

    • Bupivacaine 0.5% (3 ml) was administered to 100 patients in four groups based on post-injection position: supine, lateral, sitting, and Trendelenburg.
    • Median dermatome levels were recorded at 15 and 60 minutes post-injection.
    • Results indicated that subarachnoid bupivacaine exhibits hypobaric characteristics, consistent with in vitro findings.

    Impact:

    • The findings confirm the hypobaric nature of bupivacaine 0.5% in vivo.
    • This knowledge aids anesthesiologists in optimizing patient positioning for targeted spinal anesthesia.
    • Predicting anesthetic spread based on drug baricity and patient position improves procedural safety and effectiveness.

    Related Experiment Videos