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Related Experiment Videos

Acute sectorial choroidal ischemia.

R Spolaore, A Gaudric, G Coscas

    American Journal of Ophthalmology
    |December 15, 1984
    PubMed
    Summary
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    Temporal arteritis and carotid obstruction can cause choroidal ischemia. Retinal pigment epithelium damage is often less extensive than choroidal hypoperfusion, indicating protective mechanisms limit severe damage.

    Area of Science:

    • Ophthalmology
    • Vascular Medicine

    Background:

    • Sectorial choroidal ischemia can result from temporal arteritis or carotid obstruction.
    • Understanding the extent of retinal pigment epithelium damage versus choroidal hypoperfusion is crucial for managing ischemic events.

    Purpose of the Study:

    • To investigate the relationship between choroidal hypoperfusion and retinal pigment epithelium damage in patients with sectorial choroidal ischemia.
    • To explore potential mechanisms that mitigate ischemic damage in the choroid.

    Main Methods:

    • Fluorescein angiography was performed on four eyes from three patients during and after the acute phase of ischemia.
    • Clinical observations of retinal pigment epithelium changes were recorded.

    Main Results:

    Related Experiment Videos

  • Hypoperfusion affected the entire temporal choroid in all cases.
  • Retinal pigment epithelium disturbance was less extensive, with triangular scarring in two cases, streaks in one, and normal in one.
  • The extent of scarring did not directly correlate with the acute phase choroidal artery obstruction.

    • Conclusions:

    • Choroidal hypoperfusion in temporal arteritis or carotid obstruction may involve more than a single choroidal artery.
    • Mechanisms like venous filling and perfusion restoration can protect the retinal pigment epithelium.
    • Retinal pigment epithelium necrosis occurs only in sectors with particularly severe or prolonged ischemia.