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Intraocular pressure response to inversion.

J D LeMarr, L A Golding, J G Adler

    American Journal of Optometry and Physiological Optics
    |November 1, 1984
    PubMed
    Summary
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    Head-down inversion significantly increases intraocular pressure (IOP) and blood pressure (BP) in healthy adults. These elevated measurements return to normal upon resuming an upright stance.

    Area of Science:

    • Ophthalmology
    • Physiology

    Background:

    • Intraocular pressure (IOP) is a critical factor in ocular health.
    • Understanding physiological responses to postural changes is important for various medical fields.

    Purpose of the Study:

    • To investigate the acute effects of head-down inversion on intraocular pressure (IOP) and blood pressure (BP).

    Main Methods:

    • 26 healthy young subjects underwent 180-degree head-down inversion using a gravity inversion device.
    • IOP and BP were measured in standing, inverted, and recovery positions.

    Main Results:

    • Mean standing IOP increased from 16.4/15.9 mmHg to 34/31 mmHg upon inversion.
    • Mean standing blood pressure increased from 110/77 mmHg to 130/90 mmHg.

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  • IOP and BP remained elevated during inversion and normalized post-inversion.

    • Conclusions:

    • Head-down inversion causes a significant and rapid increase in IOP and BP.
    • These findings highlight the physiological impact of gravitational changes on ocular and systemic circulation.