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Reference values for 24 biochemical constituents of children in Singapore
Insights
Establishing pediatric reference values for 24 biochemical tests in Singaporean children is crucial for accurate patient data interpretation. This study provides these essential health benchmarks for the local pediatric population.
Area of Science:
- Biochemistry
- Pediatrics
- Clinical Pathology
Background:
- Accurate interpretation of biochemical data relies on established reference values.
- Previous difficulties prevented obtaining local pediatric reference values.
- This study addresses the need for reliable pediatric biochemical benchmarks.
Purpose of the Study:
- To establish reference values for 24 biochemical constituents in Singaporean children.
- To provide age-specific reference values for key biochemical markers.
- To compare pediatric values with established local adult reference values.
Main Methods:
- Blood specimens were collected from 352 healthy Singaporean children.
- Biochemical analysis was performed for 24 different constituents.
- Reference values were calculated for the overall pediatric group and specific age strata.
Main Results:
- Reference values for 24 biochemical constituents were successfully established for the pediatric population.
- Age-specific reference values were determined for several biochemical markers.
- Comparisons were made between pediatric and adult biochemical reference values.
Conclusions:
- The study successfully established essential reference values for pediatric biochemical testing in Singapore.
- These findings will aid in the accurate clinical interpretation of biochemical data in children.
- The established values provide a critical resource for local pediatric healthcare.
Abstract:
Reference values are essential for interpretation of biochemical data on patients. Due to various problems, such values could not be obtained for the local paediatric population. This study was carried out to establish reference values for 24 biochemical constituents using blood specimens obtained from 352 Singapore children who were assessed to be free from any disease that may affect the values. For a number of biochemical constituents, reference values were also calculated for the different age groups. These values are compared with the local adult values established by the same methods.