Transcatheter embolization of renal tumors with I-125 particles

Remarkably improved survival rates are reported in patients treated for advanced stage renal cell carcinoma by 125I interstitial infarct implant (2y = 50%, 5y = 37% survival). The interstitial implants are seated by transcatheter embolization. The salutory results particularly in patients treated for advanced stage primary lesions and bone metastases suggest the added impact of improved host immune response. The method is recommended for the management of nonresectable neoplasms, neoplasms in a solitary kidney, in patients with medical contraindications to surgical management and to convert unresectable neoplasms into resectable ones.