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Related Experiment Videos

Imperforate anus: the neurologic implication of sacral abnormalities.

J A Carson, P D Barnes, W P Tunell

    Journal of Pediatric Surgery
    |December 1, 1984
    PubMed
    Summary

    Imperforate anus patients with sacral anomalies often have hidden spinal cord lesions. Early detection and neurosurgical correction can prevent progressive bowel, bladder, and musculoskeletal dysfunction.

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    Area of Science:

    • Pediatric Surgery
    • Neurology
    • Developmental Biology

    Background:

    • The association between imperforate anus, sacral abnormalities, and neurological deficits is established.
    • Neurological deficits in these patients were historically considered static.
    • Recent observations suggest potential for progressive neurological decline due to spinal cord lesions.

    Purpose of the Study:

    • To determine the frequency of spinal cord lesions in patients with imperforate anus and sacral anomalies.
    • To investigate the potential for neurosurgical intervention in managing these conditions.
    • To advocate for routine screening for spinal cord lesions in this patient population.

    Main Methods:

    • Routine myelography was performed on patients diagnosed with imperforate anus and sacral anomalies.

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  • Analysis of imaging results to identify spinal cord abnormalities.
  • Correlation of findings with clinical presentation and potential for progressive dysfunction.

    • Main Results:

    • Thirty percent of patients with anorectal abnormalities exhibited sacral dysplasia.
    • Eight out of nine patients who underwent myelography presented with abnormal findings.
    • Identified lesions included tethered spinal cord (6 patients), spinal canal stenosis (1 patient), and anterior meningocele (1 patient).

    Conclusions:

    • A high incidence of unsuspected spinal cord lesions exists in patients with imperforate anus and sacral anomalies.
    • These lesions can lead to progressive bowel, bladder, and musculoskeletal dysfunction.
    • Routine screening for spinal cord lesions is recommended to enable timely neurosurgical intervention and prevent irreversible damage.