Related Experiment Video

Updated: Aug 11, 2026

Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure
08:17

Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure

Published on: August 25, 2017

Chronic respiratory effects of exposure to diesel emissions in coal mines

R G Ames, D S Hall, R B Reger

    Archives of Environmental Health
    |November 1, 1984
    PubMed

    More Related Videos

    Aggravation of Myocardial Ischemia upon Particulate Matter Exposure in Atherosclerosis Animal Model07:35

    Aggravation of Myocardial Ischemia upon Particulate Matter Exposure in Atherosclerosis Animal Model

    Published on: December 10, 2021

    Measuring Carbon Content in Airway Macrophages Exposed to Carbon-Containing Particulate Matters05:18

    Measuring Carbon Content in Airway Macrophages Exposed to Carbon-Containing Particulate Matters

    Published on: July 12, 2024

    Related Concept Videos

    Chronic Obstructive Pulmonary Disease01:24

    Chronic Obstructive Pulmonary Disease

    COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
    Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
    Chronic Obstructive Pulmonary Disease-I: Introduction01:20

    Chronic Obstructive Pulmonary Disease-I: Introduction

    Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.
    Chronic Obstructive Pulmonary Disease I: Introduction01:23

    Chronic Obstructive Pulmonary Disease I: Introduction

    Chronic obstructive pulmonary disease is a common, preventable, and treatable respiratory disorder characterized by persistent symptoms and progressive airflow limitation. This limitation results from a combination of small-airway disease (obstructive bronchiolitis) and parenchymal destruction (emphysema), both driven by chronic inflammation from exposure to harmful particles or gases.The disease includes two main pathological entities: emphysema, marked by destruction of alveolar walls and...
    Chronic Obstructive Pulmonary Disease II: Emphysema01:23

    Chronic Obstructive Pulmonary Disease II: Emphysema

    Emphysema, a major phenotype of chronic obstructive pulmonary disease (COPD), is characterized by irreversible destruction of alveolar walls and permanent enlargement of distal airspaces. Unlike chronic bronchitis, which primarily affects the airways, emphysema predominantly involves the lung parenchyma, where structural damage leads to airflow limitation.PathophysiologyIt most commonly results from prolonged exposure to cigarette smoke and other toxic gases, particularly cigarette smoke.
    Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features01:24

    Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features

    Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...
    Chronic Obstructive Pulmonary Disease IV: Clinical Manifestations01:19

    Chronic Obstructive Pulmonary Disease IV: Clinical Manifestations

    Chronic Obstructive Pulmonary Disease, or COPD, is a long-term condition marked by persistent and only partially reversible airflow limitation. It involves two overlapping conditions—chronic bronchitis and emphysema—which often co-appear but differ in dominant symptoms and underlying mechanisms.Chronic Bronchitis FeaturesChronic bronchitis presents with a persistent productive cough and thick, sometimes purulent mucus due to airway inflammation, enlarged mucus glands, and goblet cell...