Cancer of the endometrium stage I--standardized or individualized treatment?

Cancer of the endometrium is the most frequent gynecological cancer in many western countries. About 75% are in stage I, which comprises a wide range of tumors of different prognosis. Survival rates with any form of standardized treatment have not increased significantly in the last decades. The rationale for an individualized treatment of stage I cancers is explained and our present treatment modalities are described. It is for the future to decide whether or not such a policy is beneficial.