Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Summating potential (SP) tuning curves.

M A Cheatham, P Dallos

    Hearing Research
    |November 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Researchers explored two methods to analyze cochlear potential, the summating potential (SP). SP tuning curves and iso-response functions revealed similar frequency tuning, with iso-response functions offering an advantage by avoiding nonlinear phenomena in masking procedures.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    The remarkable cochlear amplifier.

    Hearing research·2010
    Same author

    Comment on "Mutual suppression in the 6 kHz region of sensitive chinchilla cochleae" [J. Acoust. Soc. Am. 121, 2805-2818 (2007)].

    The Journal of the Acoustical Society of America·2008
    Same author

    Evaluation of an independent prestin mouse model derived from the 129S1 strain.

    Audiology & neuro-otology·2007
    Same author

    Cochlear function in mice with only one copy of the prestin gene.

    The Journal of physiology·2005
    Same author

    Cochlear function in Prestin knockout mice.

    The Journal of physiology·2004
    Same author

    Intracellular calcium and outer hair cell electromotility.

    Brain research·2001
    Same journal

    Estimation of hair cell loss from audiograms.

    Hearing research·2026
    Same journal

    Cochlear size variation in a large-scale international multicentre cohort.

    Hearing research·2026
    Same journal

    Estimation of minor-to-moderate conductive hearing loss with distortion-product otoacoustic emissions in humans.

    Hearing research·2026
    Same journal

    Effects of early hearing deficits on olivocochlear efferent neuron morphology in mice.

    Hearing research·2026
    Same journal

    Cochlear aging after synaptopathic noise: age-noise interactions in hair cell loss and axonal degeneration.

    Hearing research·2026
    Same journal

    MERGE: Misophonia and emotion regulation in a guided experience sampling study.

    Hearing research·2026
    See all related articles

    Area of Science:

    • Auditory Neuroscience
    • Otoacoustic Emissions
    • Sensory Physiology

    Background:

    • The summating potential (SP) is a gross d.c. cochlear potential reflecting auditory nerve activity.
    • Understanding frequency-specific information from SP is crucial for diagnosing hearing disorders.
    • Previous methods for SP analysis have limitations in accuracy and susceptibility to nonlinear artifacts.

    Purpose of the Study:

    • To compare two distinct methods for extracting frequency-specific information from the summating potential (SP).
    • To evaluate the influence of parameter variations on SP tuning characteristics.
    • To assess the degree of cochlear tuning reflected by SP measurements.

    Main Methods:

    • Derivation of SP tuning curves using a two-tone simultaneous masking procedure.

    Related Experiment Videos

  • Obtention of SP iso-response functions.
  • Investigation of parameter changes' influence on SP function configurations.

    • Main Results:

    • SP tuning curves exhibited higher Q10 dB values than SP iso-response functions at the cochlear base.
    • SP iso-response functions demonstrated an advantage by avoiding nonlinear phenomena present in simultaneous tone-on-tone masking.
    • SP tuning curves showed similarity to basilar membrane motion and whole nerve action potential (AP) tuning.

    Conclusions:

    • Both SP tuning curves and iso-response functions reflect frequency-specific cochlear tuning.
    • SP iso-response functions provide a more robust measure by mitigating nonlinear masking effects.
    • The findings suggest that SP recordings capture a similar degree of peripheral cochlear tuning as other established measures.