Synthesis of some bergapten and ammajin derivatives with potential antibacterial activity

The reaction of bergapten and ammajin with chlorosulfonic acid i shown to give the sulfonyl chlorides 1 and 11 which react with aliphatic, aromatic, and heterocyclic amines to give the corresponding sulfonamides. Phenols also react with 1 and 11 to give the sulfonate esters 5 and 15. Interaction of bergapten with phosphorous(V)sulfide gave the thione 7 which on reaction with amines gave 9. The antibacterial activity of the products is reported.