Tissue reaction to a failed Bion hip prosthesis in a dog

The tissue reaction in a dog to a failed constrained total hip replacement system with a Bion elastomer component was evaluated. The device consisted of Ti-6A1-4V alloy acetabular and femoral components connected with a Bion component. At necropsy the Bion component was found to have fractured. The tissue surrounding the Bion was granulomatous with numerous blackened regions. Histologically a severe chronic inflammatory response was present in the surrounding tissue with numerous giant cells and Bion laden macrophages.