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Related Experiment Videos

A new device for administering placebo alcohol.

J H Mendelson, M McGuire, N K Mello

    Alcohol (Fayetteville, N.Y.)
    |September 1, 1984
    PubMed
    Summary

    A new device delivered placebo alcohol, causing intoxication in most participants. This suggests expectancy plays a key role in perceived alcohol effects, aiding future alcohol studies.

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    Area of Science:

    • Psychopharmacology
    • Neuroscience
    • Human Physiology

    Background:

    • Expectancy effects significantly influence subjective experiences, including those related to alcohol consumption.
    • Accurate placebo controls are crucial for isolating the pharmacological effects of alcohol in research.
    • Developing reliable methods for placebo alcohol administration is essential for advancing alcohol research.

    Purpose of the Study:

    • To evaluate a novel device for administering placebo alcohol.
    • To assess the degree of intoxication induced by placebo alcohol.
    • To investigate the role of expectancy in perceived alcohol intoxication.

    Main Methods:

    • Healthy adult males received placebo alcohol via a new administration device.
    • Participants self-reported intoxication levels.
    • Blood alcohol content (BAC) was monitored, reaching a peak of 84 mg/dl.

    Main Results:

    • Placebo alcohol induced a sense of intoxication in 70% (7 of 10) of participants.
    • Subjective intoxication ratings after placebo alcohol were 36% of those reported after real alcohol consumption.
    • Peak BAC levels during placebo administration reached 84 mg/dl.

    Conclusions:

    • The novel device effectively administered placebo alcohol, inducing measurable intoxication.
    • Expectancy significantly contributes to perceived intoxication, highlighting the importance of placebo controls in alcohol studies.
    • This device offers a valuable tool for future research on alcohol effects and expectancy.

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