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[Gastrointestinal involvement in progressive systemic sclerosis].

M G Alvarez, R E Rubaldo, E M Kerzberg

    Acta Gastroenterologica Latinoamericana
    |January 1, 1984
    PubMed
    Summary
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    This study on systemic sclerosis (SSc) patients found high rates of esophageal dysfunction, even without symptoms. Early manometric diagnosis is key for managing gastrointestinal (GI) involvement.

    Area of Science:

    • Gastroenterology
    • Rheumatology
    • Internal Medicine

    Background:

    • Systemic sclerosis (SSc) frequently affects the gastrointestinal (GI) tract.
    • Esophageal and intestinal involvement are common, but other GI areas can also be affected.
    • Early detection and management are crucial due to the lack of ethiological therapies.

    Purpose of the Study:

    • To review gastrointestinal involvement in SSc patients, focusing on esophageal manifestations.
    • To assess the relationship between skin and GI tract involvement in SSc.
    • To highlight the diagnostic utility of manometry for esophageal motor dysfunction.

    Main Methods:

    • Retrospective review of 25 SSc patients with clinical, radiological, and manometrical GI features.
    • Detailed analysis of esophageal involvement, including functional and structural alterations.

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  • Correlation of skin disease evolution with GI tract involvement.

    • Main Results:

    • No clear relationship was observed between the progression of skin and GI tract involvement.
    • A high incidence of esophageal involvement was detected, particularly functional alterations, often asymptomatic.
    • Manometric evaluation proved useful for diagnosing esophageal motor disorders, especially lower esophageal sphincter dysfunction.

    Conclusions:

    • Esophageal functional alterations are common in SSc patients, underscoring the need for manometric assessment.
    • Early identification of GI involvement, including asymptomatic esophageal dysfunction, is vital for timely symptomatic treatment.
    • Comprehensive evaluation of the entire GI tract is important in SSc management.