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Related Experiment Videos

Spontaneous partial empty sella. A study of 41 cases.

A Jara-Albarrán, J Bayort, M De Juan

    Experimental and Clinical Endocrinology
    |March 1, 1984
    PubMed
    Summary

    Partial empty sella turcica is often linked to pituitary hyperfunction or neurological issues, not idiopathic causes. Accurate terminology like "hypothyroidism with empty sella" improves patient prognosis and treatment.

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    Area of Science:

    • Endocrinology
    • Neurology
    • Radiology

    Background:

    • Partial empty sella turcica is a condition affecting the pituitary gland.
    • The etiology of this condition has been debated, particularly the term 'primary' empty sella.

    Purpose of the Study:

    • To investigate the clinical and radiological findings in partial empty sella turcica.
    • To re-evaluate the classification and terminology of primary partial empty sella turcica.
    • To highlight the importance of accurate diagnosis for patient management.

    Main Methods:

    • Clinical and radiological evaluation of 53 cases of partial empty sella turcica.
    • Exclusion of cases with incomplete endocrine assessments.
    • Review of published literature on primary partial empty sella.

    Main Results:

    • Of 41 evaluated cases, 75.6% showed adenohypophyseal hyperfunction (e.g., hypothyroidism, acromegaly).
    • 9.7% had a neurological cause (e.g., head trauma, sinus thrombosis).
    • Only 14.6% were of unknown or idiopathic origin.

    Conclusions:

    • The term 'spontaneous' is preferred over 'primary' for empty sella.
    • Most cases are secondary to pituitary hyperfunction or neurological factors.
    • Accurate diagnostic terminology, such as 'hypothyroidism with partial empty sella turcica', is crucial for prognosis and treatment.

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