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Respiratory dysautonomia in leprosy.
Indian Journal of Leprosy
|October 1, 1984
Summary
Leprosy can affect the autonomic nervous system, specifically impacting respiratory functions. Nearly half of polar lepromatous leprosy patients studied showed impaired sympathetic respiratory reflexes.
Area of Science:
- Neurology
- Infectious Diseases
- Physiology
Background:
- Autonomic neuropathy is an emerging complication in leprosy.
- Leprosy, particularly the lepromatous form, can affect various nerve functions.
Purpose of the Study:
- To investigate respiratory dysautonomia in patients with polar lepromatous leprosy.
- To assess the involvement of sympathetic respiratory reflexes in leprosy patients.
Main Methods:
- Studied 25 cases of polar lepromatous leprosy (with and without lepra reaction).
- Included 25 healthy individuals as a control group.
- Evaluated respiratory dysautonomia and sympathetic respiratory reflexes.
Main Results:
- 48% (12 out of 25) of leprosy patients exhibited involvement of sympathetic respiratory reflexes.
- This suggests a significant prevalence of respiratory autonomic dysfunction in this patient group.
Conclusions:
- Autonomic neuropathy, specifically affecting respiratory reflexes, is a notable complication in polar lepromatous leprosy.
- Further research is needed to explore the underlying causes and clinical implications.