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Supravalvular aortic stenosis with parafollicular cell (C-cell) hyperplasia
The American Journal of Medicine
|June 1, 1978
Summary
Idiopathic infantile hypercalcemia syndrome involves C-cell hyperplasia, leading to increased calcitonin. This suggests augmented thyrocalcitonin activity in response to elevated serum calcium levels.
Area of Science:
- Endocrinology
- Pathology
- Pediatric Syndromes
Background:
- Idiopathic infantile hypercalcemia syndrome presents with supravalvular aortic stenosis and other characteristic features.
- The underlying biochemical defect and systemic pathology remain incompletely understood.