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Related Experiment Videos

Silicon, fibre, and atherosclerosis.

K Schwarz

    Lancet (London, England)
    |February 26, 1977
    PubMed
    Summary

    Dietary silicon, particularly silicate-silicon found in fiber, may be crucial in preventing atherosclerosis. Low silicon intake, common in refined foods, could increase cardiovascular disease risk.

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    Area of Science:

    • Biochemistry
    • Cardiovascular Science
    • Nutrition

    Background:

    • Silicon, in the form of silicic acid, is essential for growth and acts as a cross-linking agent in connective tissues.
    • The arterial wall, particularly the intima, contains unusually high amounts of bound silicon.
    • Atherosclerosis is a cardiovascular disease characterized by the buildup of plaques in arteries.

    Purpose of the Study:

    • To investigate the hypothesis that a lack of silicon may be an important etiological factor in atherosclerosis.
    • To explore the role of silicon in dietary fiber and its potential impact on cardiovascular health.

    Main Methods:

    • Analysis of silicon content in various dietary fiber products.
    • Correlation of silicon levels in fiber with their reported efficacy in preventing experimental atherosclerosis.
    • Comparison of silicon content in refined versus crude food products.

    Main Results:

    • Dietary fiber products effective against experimental atherosclerosis contained exceptionally large amounts of silicon (1000-25,000 p.p.m.).
    • Inactive materials like purified cellulose had negligible silicon content.
    • Refined products (white flour, soy) showed significantly lower silicon levels than their crude counterparts.

    Conclusions:

    • Silicate-silicon in dietary fiber is likely the active agent influencing atherosclerosis development.
    • Lower dietary silicon availability, due to industrial food processing, may contribute to atherosclerosis incidence.
    • The low incidence of atherosclerosis in less developed countries might be linked to higher dietary silicon intake.

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