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[Bilateral malignant Brenner's tumor. Apropos of a case]
Revista Espanola De Oncologia
|January 1, 1984
Summary
A rare malignant Brenner tumor in a 51-year-old woman was treated with chemotherapy. Post-treatment assessments confirmed the absence of malignant cells, indicating successful management of this rare ovarian cancer.
Area of Science:
- Gynecologic Oncology
- Pathology
Background:
- Brenner tumors are rare epithelial ovarian neoplasms, typically benign, but malignant variants can occur.
- Malignant Brenner tumors (MBTs) represent a small subset of ovarian cancers with distinct clinical and pathological features.
Observation:
- A 51-year-old woman presented with a year of pelvic fullness, pain, anorexia, asthenia, and weight loss.
- Gynecological examination revealed a vaginal mass and a right adnexal mass.
- Surgical resection led to the diagnosis of a malignant Brenner tumor.
Findings:
- Postoperative chemotherapy was initiated for the malignant Brenner tumor.
- Initial "second-look" surgery was macroscopically negative but cytologically positive for malignancy.
- A second course of chemotherapy was administered, resulting in negative macroscopic and cytologic findings in the subsequent "second-look" surgery.
Implications:
- This case highlights the importance of thorough evaluation and multimodal treatment for malignant Brenner tumors.
- Effective management may involve surgery followed by chemotherapy, with close cytologic monitoring.
- Complete remission achieved after treatment suggests a favorable prognosis with appropriate therapeutic interventions.