Enamel fluoride content after using amine fluoride- or monofluorophosphate-sodium fluoride-dentifrices

The fluoride retention in enamel was determined in vivo comparing the short-term unsupervised use of amine fluoride- and monofluorophosphate-sodium fluoride-dentifrices. Acid-etch enamel biopsies in the double-blind study showed that the fluoride content in enamel was significantly higher following use of the amine fluoride dentifrice, 959 ppm F vs 330 ppm F. Both dissolution of the enamel, determined by the amount of phosphorus (33.9 micrograms vs 50.9 micrograms) and the depth of etch (6.2 microns vs 9.6 microns) were significantly reduced after use of the amine fluoride compared to the monofluorophosphate-sodium fluoride combination.