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Migration of K562 cells and its inhibition by lymphokines
Abstract:
Cells of the human myelogenous line K562 migrate from glass capillaries to the glass or plastic surface of culture flasks in the presence of RPMI 1640. Like macrophages they form a halo around the opening of the capillary. Migration is inhibited by lymphokine-containing supernatants from mixed lymphocyte culture (MLC). Concanavalin A stimulated lymphocytes and from several cell lines.